The principal modifiable risk factors for stroke are hypertension, diabetes mellitus, hypercholesterolaemia, hyperhomocysteinaemia, smoking and limited physical activity. However, it is not clear whether physical inactivity is a risk factor per se, or because it predisposes to pathological conditions that are risk factors for stroke. The limited availability of effective therapeutic approaches for stroke emphasizes the crucial role of prevention of risk factors. The global burden associated with type 2 diabetes is large and continues to grow. Convincing epidemiologic data support the role of physical activity in preventing type 2 diabetes. The increasing evidence of physical activity in preventing diabetic complications, including stroke, has generated interest in the molecular basis underlying these beneficial effects. The aim of the present review is to discuss the biological mechanisms underlying the effect of physical activity in preventing stroke in type 2 diabetes.

(2009). Biological mechanisms of stroke prevention by physical activity in type 2 diabetes [journal article - articolo]. In ACTA NEUROLOGICA SCANDINAVICA. Retrieved from http://hdl.handle.net/10446/159811

Biological mechanisms of stroke prevention by physical activity in type 2 diabetes

Agosti, V.;
2009-01-01

Abstract

The principal modifiable risk factors for stroke are hypertension, diabetes mellitus, hypercholesterolaemia, hyperhomocysteinaemia, smoking and limited physical activity. However, it is not clear whether physical inactivity is a risk factor per se, or because it predisposes to pathological conditions that are risk factors for stroke. The limited availability of effective therapeutic approaches for stroke emphasizes the crucial role of prevention of risk factors. The global burden associated with type 2 diabetes is large and continues to grow. Convincing epidemiologic data support the role of physical activity in preventing type 2 diabetes. The increasing evidence of physical activity in preventing diabetic complications, including stroke, has generated interest in the molecular basis underlying these beneficial effects. The aim of the present review is to discuss the biological mechanisms underlying the effect of physical activity in preventing stroke in type 2 diabetes.
articolo
2009
Agosti, Valeria; Graziano, S.; Artico, L.; Sorrentino, G.
(2009). Biological mechanisms of stroke prevention by physical activity in type 2 diabetes [journal article - articolo]. In ACTA NEUROLOGICA SCANDINAVICA. Retrieved from http://hdl.handle.net/10446/159811
File allegato/i alla scheda:
File Dimensione del file Formato  
2009-Biological mechanisms of Stroke Prevention by Physical Activity in Type 2 Diabetes.pdf

Solo gestori di archivio

Versione: publisher's version - versione editoriale
Licenza: Licenza default Aisberg
Dimensione del file 297.89 kB
Formato Adobe PDF
297.89 kB Adobe PDF   Visualizza/Apri
Pubblicazioni consigliate

Aisberg ©2008 Servizi bibliotecari, Università degli studi di Bergamo | Terms of use/Condizioni di utilizzo

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10446/159811
Citazioni
  • Scopus 14
  • ???jsp.display-item.citation.isi??? 9
social impact