It is very difficult to find analytical information about nabilone in the literature. To our knowledge this is the first HPLC/MS/MS study of nabilone with a TurboIonSpray source. The method developed here permitted the detection and quantitation of nabilone in bulk powders and capsules. The very good sensitivity (LOD 1⁄4 1 pg of nabilone injected) of the developed method suggests further studies of trace detection of this compound in biological samples using HPLC/MS/ MS, after developing a suitable extraction procedure.
(2004). Determination of nabilone in bulk powders and capsules by high-performance liquid chromatography/tandem mass spectrometry [journal article - articolo]. In RAPID COMMUNICATIONS IN MASS SPECTROMETRY. Retrieved from http://hdl.handle.net/10446/145578
Determination of nabilone in bulk powders and capsules by high-performance liquid chromatography/tandem mass spectrometry
Romolo, Francesco Saverio;
2004-01-01
Abstract
It is very difficult to find analytical information about nabilone in the literature. To our knowledge this is the first HPLC/MS/MS study of nabilone with a TurboIonSpray source. The method developed here permitted the detection and quantitation of nabilone in bulk powders and capsules. The very good sensitivity (LOD 1⁄4 1 pg of nabilone injected) of the developed method suggests further studies of trace detection of this compound in biological samples using HPLC/MS/ MS, after developing a suitable extraction procedure.| File | Dimensione del file | Formato | |
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