Renal fibrosis, which is characterized by the progressive deposition and accumulation of excess extracellular matrix,1 is a strong predictor of progression in chronic kidney disease (CKD).2,3 Recent advances in diagnostic imaging techniques, including ultrasonography and noncontrast-enhanced magnetic resonance imaging (MRI), have shown promise for noninvasive assessment of renal fibrosis both in animals and humans.4 However, the specificity of these techniques is controversial, because they indirectly assess renal fibrosis by evaluating the impact on mechanical or molecular properties of the tissue, and in the case of functional MRI, on kidney function.

(2020). Does MRI trump pathology? A new era for staging and monitoring of kidney fibrosis [journal article - articolo]. In KIDNEY INTERNATIONAL. Retrieved from http://hdl.handle.net/10446/150732

Does MRI trump pathology? A new era for staging and monitoring of kidney fibrosis

Remuzzi, Andrea;
2020-01-01

Abstract

Renal fibrosis, which is characterized by the progressive deposition and accumulation of excess extracellular matrix,1 is a strong predictor of progression in chronic kidney disease (CKD).2,3 Recent advances in diagnostic imaging techniques, including ultrasonography and noncontrast-enhanced magnetic resonance imaging (MRI), have shown promise for noninvasive assessment of renal fibrosis both in animals and humans.4 However, the specificity of these techniques is controversial, because they indirectly assess renal fibrosis by evaluating the impact on mechanical or molecular properties of the tissue, and in the case of functional MRI, on kidney function.
articolo
2020
Caroli, Anna; Remuzzi, Andrea; Remuzzi, Giuseppe
(2020). Does MRI trump pathology? A new era for staging and monitoring of kidney fibrosis [journal article - articolo]. In KIDNEY INTERNATIONAL. Retrieved from http://hdl.handle.net/10446/150732
File allegato/i alla scheda:
File Dimensione del file Formato  
document(7).pdf

Solo gestori di archivio

Versione: publisher's version - versione editoriale
Licenza: Licenza default Aisberg
Dimensione del file 323.89 kB
Formato Adobe PDF
323.89 kB Adobe PDF   Visualizza/Apri
Pubblicazioni consigliate

Aisberg ©2008 Servizi bibliotecari, Università degli studi di Bergamo | Terms of use/Condizioni di utilizzo

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10446/150732
Citazioni
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 13
social impact