This paper introduces SIMSPIRE, a comprehensive simulator of the human respiratory system designed as a versatile tool for simulating various patient conditions. It can be used to model patients with a wide range of physiological traits, such as varying lung compliance and resistance, as well as respiratory conditions, such as chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS). The versatility of SIMSPIRE makes it suitable for simulating diverse respiratory scenarios and evaluating new algorithms or control strategies for ventilatory support. For this work, we have tested and evaluated our simulator by connecting as input the control software of a ventilator prototype. SIMSPIRE represents a significant advancement in the field of respiratory simulation. It provides a highly accurate and customizable platform for improving the design of ventilation systems and optimizing patient outcomes. By eliminating the need for expensive hardware simulators, SIMSPIRE has the potential to accelerate innovation and contribute to enhanced patient care in critical care settings.

(2025). SIMSPIRE: A Simulator of the Respiratory System [journal article - articolo]. In IEEE ACCESS. Retrieved from https://hdl.handle.net/10446/304425

SIMSPIRE: A Simulator of the Respiratory System

Bombarda, Andrea;Bonfanti, Silvia;Gargantini, Angelo;
2025-01-01

Abstract

This paper introduces SIMSPIRE, a comprehensive simulator of the human respiratory system designed as a versatile tool for simulating various patient conditions. It can be used to model patients with a wide range of physiological traits, such as varying lung compliance and resistance, as well as respiratory conditions, such as chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS). The versatility of SIMSPIRE makes it suitable for simulating diverse respiratory scenarios and evaluating new algorithms or control strategies for ventilatory support. For this work, we have tested and evaluated our simulator by connecting as input the control software of a ventilator prototype. SIMSPIRE represents a significant advancement in the field of respiratory simulation. It provides a highly accurate and customizable platform for improving the design of ventilation systems and optimizing patient outcomes. By eliminating the need for expensive hardware simulators, SIMSPIRE has the potential to accelerate innovation and contribute to enhanced patient care in critical care settings.
silvia.bonfanti@unibg.it
articolo
2025
Inglese
online
13
113428
113437
Settore IINF-05/A - Sistemi di elaborazione delle informazioni
Human system modeling; mechanical ventilator testing; medical software certification; medical software testing; respiratory system; simulator; test-driven development;
   SAFEST: Trust assurance of Digital Twins for medical cyber-physical systems
   SAFEST
   MUR - MINISTERO DELL'UNIVERSITA' E DELLA RICERCA - Segretariato generale Direzione generale della ricerca - Ufficio IV
   20224AJBLJ_01
Bombarda, Andrea; Bonfanti, Silvia; Gargantini, Angelo Michele; Riccobene, Elvinia
info:eu-repo/semantics/article
open
(2025). SIMSPIRE: A Simulator of the Respiratory System [journal article - articolo]. In IEEE ACCESS. Retrieved from https://hdl.handle.net/10446/304425
Non definito
4
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10446/304425
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